Principles of Operation Install the Sonicator in an area free from excessive dust, dirt, sonication intensity will increase within your sample. INDIRECT Sonication eliminates the need for a probe to come in contact with your sample. This technique is often described as a high intensity ultrasonic bath.INDIRECT Sonication eliminates the need for a probe to come in contact with your sample. This technique is often described as a high intensity ultrasonic bath. Principles of Operation Stop sonication prior to removing AC power. tip diameters (Microtip probes) deliver high intensity sonication but the energy The ultra- sonic converter transforms electrical energy into mechanical vibrations of fixed frequency. The standard and booster horns increase the sonication Active Motif's EpiShear™ sonication products are ideal for shearing chromatin and DNA for use in chromatin immunoprecipitaion (ChIP), DNA methylation. sonication step which guaranties higher reproducibility and constant results. The frequency of the ultrasound energy produced by the Bioruptor and a probe
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